General Information
| Application | Inhibitor |
|---|
| Cas NO. |
521984-48-5 |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 489.99 |
| Formula | C28H27N3O3.HCl |
| Solubility |
DMSO : 97mg/ml Ethanol : 24mg/ml H2O : Insoluble |
|---|
| Description | SIS3, a novel specific inhibitor of Smad3, inhibits TGF-β and active signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways. |
|---|
| Target / IC50 | Smad3 |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 2 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.0409 mL |
10.2043 mL |
20.4086 mL |
|
| 5 mM | 0.4082 mL | 2.0409 mL | 4.0817 mL | |
| 10 mM | 0.2041 mL | 1.0204 mL | 3.7414 mL | |
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