PAKα/β/γ (phospho Ser144/141/139) Polyclonal Antibody
- Catalog Number : A27148PI
- Number : A27148PI-20ug
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Introduction
p21 (RAC1) activated kinase 1(PAK1) Homo sapiens This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK
proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for
the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for
the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
General Information
| Reactivity | Human, Mouse, Rabbit |
|---|---|
| Application | WB, ELISA, IHC-p |
| Host | Rabbit |
| Clonality | Polyclonal |
| Uniprot | Q13153/Q13177/O75914 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PAK1/2/3 around the phosphorylation site of Ser144/141/139. AA range:111-160 |
| Assay principle | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Molecular Weight | 65 KD |
| Formula | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instruction | -20°C/1 year |
| Alias | PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK; PAK2; Serine/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58; PAK3; OPHN3; Serine/threonine-p |
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