anti-IL-6R (Tocilizumab)
- Catalog Number : A510031
- Number : A510031-1mg
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Size:
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Introduction
Tocilizumab is a recombinant humanized anti-human interleukin 6 (IL-6) receptor monoclonal antibody of the immunoglobulin IgG1κ (gamma 1, kappa) subclass with a typical H2L2 polypeptide structure. Each light chain and heavy chain consists of 214 and 448 amino acids, respectively. The four polypeptide chains are linked intra- and inter-molecularly by disulfide bonds.
General Information
| Reactivity | Human |
|---|---|
| Application | Functional Assay |
| Host | CHO cells |
| Clonality | Monoclonal |
| Conjugate | Non-conjugated |
| Isotype | Human IgG1 |
| Cas No. | 375823-41-9 |
| Purity | >95%; < 0.75 EU/mg as determined by the LAL method |
| Molecular Weight | 148 kDa |
| Storage buffer | 0.01 M phosphate buffered saline (PBS) pH 7.2 |
| Storage instruction | This solution is stable for at least 4 weeks when stored at 2-8°C. For long term storage aseptically aliquot and store at –80°C.Avoid repeated freeze/thaw cycles. |
| Alias | MRA, Atlizumab |
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