Polymyxin B sulfate
- Catalog Number : AN0015
- Number : AN0015-1g
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Size:
Qty : - Price : Request Inquiry
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Introduction
Polymyxin B is one of the most important antibiotics used to treat gram-negative bacterial infections, including infections caused by carbapenem-resistant non-fermenters and carbapenem-resistant Enterobacteriaceae. Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides?, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.
General Information
| Cas No. | 1405-20-5 |
|---|---|
| Molecular Weight | 1385.61 |
| Formula | C55H96N16O13·2H2SO4 |
| Solubility | Soluble in water at 50mg/ml/n |
| Storage instruction | Store at 2-8℃ and protect from light |
| Grade |
USP Grade |
|---|
| Titer |
≥6000u/mg |
|---|
| Appearance |
white or yellow Powder |
|---|
|
pH |
5.0～7.0 |
|---|
| Specific rotation |
-78～-90º |
|---|
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