COVID-19 
, COVID-19 Related Compounds
Gemcitabine HCl (Gemzar,LY188011)
- Catalog Number : C5119
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Introduction
Gemcitabine hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available For DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) For the detailed information about the solubility of Gemcitabine HCl (Gemzar, LY188011) in water, the solubility of Gemcitabine HCl (Gemzar, LY188011) in DMSO, the solubility of Gemcitabine HCl (Gemzar, LY188011) in PBS buffer, the animal experiment（test） of Gemcitabine HCl (Gemzar, LY188011),the in vivo,in vitro and clinical trial test of Gemcitabine HCl (Gemzar, LY188011),the cell experiment（test） of Gemcitabine HCl (Gemzar, LY188011),the IC50, EC50 and Affinity of Gemcitabine HCl (Gemzar, LY188011), please contact DC Chemicals.
General Information
| Cas No. | 122111-03-9 |
|---|---|
| Purity | >98% |
| Molecular Weight | 299.66 |
| Formula | C9H11F2N3O4.HCI |
| Solubility | DMF: 2.5 mg/mL/ DMSO: 46.67 mg/mL/ H2O : 66.66 mg/mL |
| Storage instruction | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
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