SNCA Polyclonal Antibody
- Catalog Number : A340684
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Introduction
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
General Information
Reactivity | Rat, Mouse |
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Application | WB, IF, IHC, ELISA |
Clonality | Polyclonal |
Conjugate | Non-conjugated |
Uniprot | P37840 |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human Synuclein-α around the non-phosphorylation site of Tyr133. |
Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
Alias | Alpha synuclein,Alpha-synuclein,Alpha-synuclein,isoform NACP140,alphaSYN,MGC105443,MGC110988,MGC127560,MGC64356,NACP,Non A beta component of AD amyloid,Non A4 component of amyloid,Non A4 component of amyloid precursor,Non-A beta component of AD amyloid,Non-A-beta component of alzheimers disease amyloid,precursor of,Non-A4 component of amyloid precursor,Non-A4 component of amyloid,precursor of,OTTHUMP00000218549,OTTHUMP00000218551,OTTHUMP00000218552,OTTHUMP00000218553,OTTHUMP00000218554,PARK 1,PARK 4,PARK1,PARK4,Parkinson disease (autosomal dominant,Lewy body) 4,Parkinson disease familial 1,SNCA,Snca synuclein,alpha (non A4 component of amyloid precursor),SYN,Synuclein alpha,Synuclein alpha 140,Synuclein,alpha (non A4 component of amyloid precursor),SYUA |