Phospho-PAK1 (Ser204) Polyclonal Antibody

Catalog Number : A340360
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Introduction

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

General Information

Reactivity	Rat, Mouse
Application	WB, IHC, ELISA
Clonality	Polyclonal
Conjugate	Non-conjugated
Uniprot	Q13153
Isotype	IgG
Immunogen	Synthesized peptide derived from human PAKα around the phosphorylation site of S204.
Storage buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction	Store at -20℃. Avoid freeze / thaw cycles.
Alias	ADRB2,Alpha PAK,Alpha-PAK,MGC130000,MGC130001,p21 activated kinase 1,p21 protein (Cdc42/Rac) activated kinase 1,p21-activated kinase 1,p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related),p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog,yeast),p65 PAK,p65-PAK,P68-PAK,PAK alpha,PAK-1,Pak1,PAK1,Paka,PAKalpha,Protein kinase MUK2,Rac/p21-activated kinase,Serine/threonine-protein kinase PAK 1,STE20 homolog yeast