Primary Antibody

SOCS3 Polyclonal Antibody

  • Catalog Number : A340106
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Introduction

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

General Information

Reactivity Rat, Mouse
Application WB, IHC, ELISA
Clonality Polyclonal
Conjugate Non-conjugated
Uniprot O14543
Immunogen A synthetic peptide of human SOCS3
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Alias ATOD4,CIS 3,CIS-3,CIS3,Cish3,Cytokine induced SH2 protein 3,Cytokine-inducible SH2 protein 3,E2a Pbx1 target gene in fibroblasts 10,EF 10,MGC71791,SOCS 3,SOCS-3,Socs3,SOCS3,SSI 3,SSI-3,SSI3,STAT induced STAT inhibitor 3,STAT-induced STAT inhibitor 3,Suppressor of cytokine signaling 3

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