SOCS3 Polyclonal Antibody
- Catalog Number : A340106
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Introduction
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
General Information
Reactivity | Rat, Mouse |
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Application | WB, IHC, ELISA |
Clonality | Polyclonal |
Conjugate | Non-conjugated |
Uniprot | O14543 |
Immunogen | A synthetic peptide of human SOCS3 |
Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
Alias | ATOD4,CIS 3,CIS-3,CIS3,Cish3,Cytokine induced SH2 protein 3,Cytokine-inducible SH2 protein 3,E2a Pbx1 target gene in fibroblasts 10,EF 10,MGC71791,SOCS 3,SOCS-3,Socs3,SOCS3,SSI 3,SSI-3,SSI3,STAT induced STAT inhibitor 3,STAT-induced STAT inhibitor 3,Suppressor of cytokine signaling 3 |