Introduction
Pepstatin A is an inhibitor of acid proteases (aspartyl peptidases). It forms a 1:1 complex with proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B (Aspergillus niger). The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases. Solubilized γ-secretase and retroviral protease are also inhibited by Pepstatin A.
General Information
| Application | Chemical, Inhibitor |
|---|---|
| Cas No. | 26305-03-3 |
| Purity | ≥75% (HPLC) |
| Molecular Weight | 685.90 |
| Formula | C34H63N5O9 |
| Solubility | 9 :1 = methanol : acetic acid : 1 mg/ml；Ethanol : 1-2 mg/ml with heat up to 60℃；DMSO : 5 mg/ml；Insoluble in benzene, chloroform, water, 1 M NaOH and ether. |
| Alias | Pepstatin |
.png)