General Information
| Application | Inhibitor |
|---|
| Description | Mocetinostat (MGCD0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Phase 1/2. |
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| Cas NO. | 726169-73-9 |
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| Purity | ≥98% |
|---|---|
| Molecular Weight |
396.44 |
| Formula | C23H20N6O |
| Solubility |
DMSO : 13 mg/ml Water : <1 mg/ml Ethanol: <1 mg/ml |
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| Alias | N/A |
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| Target / IC50 |
HDAC1 : 0.15 μM HDAC2 : 0.29 μM HDAC11 : 0.59 μM HDAC3 : 1.66 μM |
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| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 6 months |
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|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.5224 mL | 12.6122 mL | 25.2245 mL | |
| 5 mM | 0.5045 mL | 2.5224 mL | 5.0449 mL | |
| 10 mM | 0.2522 mL | 1.2612 mL | 2.5224 mL | |
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