General Information
| Application | Inhibitor |
|---|
| Description | CFI-400945 is an orally active, potent and selective polo-like kinase 4(PLK4) inhibitor with Ki value of 0.26 nM. |
|---|---|
| Cas NO. | 1338806-73-7 |
| Purity | ≥98% |
|---|---|
| Molecular Weight | 534.65 |
| Formula | C33H34N4O3 |
| Solubility |
DMSO : 100 mg/mL Ethanol : 100 mg/mL Water : Insoluble |
|---|
| Alias | N/A |
|---|
| Target / IC50 |
PLK4 : 2.8 nM TrkA : 6 nM TrkB : 9 nM Tie-2 22 nM Aurora B : 98 nM |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
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1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.8704 mL | 9.3519 mL | 18.7038 mL | |
| 5 mM | 0.3741 mL | 1.8704 mL | 3.7408 mL | |
| 10 mM | 0.1870 mL | 0.9352 mL | 1.8704 mL | |
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