General Information
| Application | Inhibitor |
|---|
| Description | THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7. |
|---|
| Cas NO. | 1604810-83-4 (free base) |
|---|
| Purity | ≥98% |
|---|---|
| Molecular Weight | 638.97 |
| Formula | C31H30Cl3N7O2 |
| Solubility |
DMSO : 100 mg/mL Ethanol : Insoluble Water : Insoluble |
|---|
| Alias | N/A |
|---|
| Target / IC50 |
CDK7 : 3.2 nM |
|---|
| Storage |
Powder : -20°C for 3 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
1.5650 mL | 7.8251 mL | 15.6505 mL | |
| 5 mM | 0.3130 mL | 1.5650 mL | 3.1300 mL | |
| 10 mM | 0.1565 mL | 0.7825 mL | 1.5650 mL | |
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