General Information
| Application | Inhibitor |
|---|
| Cas NO. |
1173097-76-1 |
|---|
| Description | U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD098059. |
|---|
| Purity | ≥97% |
|---|---|
| Molecular Weight | 426.56 |
| Formula | C20H22N6O2S2 |
| Solubility |
DMSO : 83 mg/ml Ethanol : Insoluble H2O : Insoluble |
|---|
| Target / IC50 | MEK 1/2 : 70/60 nM |
|---|
| Storage |
Powder : -20°C for 3 years Solvent : -80°C for 2 years |
|---|
|
|
1 mg |
5 mg |
10 mg |
|
|
1 mM |
2.3443 mL |
11.7217 mL |
23.4434 mL |
|
|
5 mM |
0.44689 mL |
2.3443 mL |
4.6887 mL |
|
|
10 mM |
0.2344 mL |
1.1722 mL |
2.3443 mL |
|
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