Primary Antibody

BECN1 Polyclonal Antibody

  • Catalog Number : A340741
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Introduction

Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

General Information

Reactivity Mouse
Application WB
Clonality Polyclonal
Conjugate Non-conjugated
Uniprot Q14457
Isotype IgG
Immunogen Synthesized peptide derived from Beclin-1
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Alias APG6,ATG 6,ATG6,ATG6 autophagy related 6 homolog,Bcl-2-interacting protein beclin,Beclin 1 (coiled coil moesin like BCL2 interacting protein),Beclin 1 autophagy related,Beclin-1,Beclin1,BECN 1,Becn1,BECN1,Coiled coil myosin like BCL2 interacting protein,Coiled-coil myosin-like BCL2-interacting protein,GT197,Protein GT197,VPS 30,VPS30

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