HDAC7 Polyclonal Antibody
- Catalog Number : A340545
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Introduction
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q8WUI4 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human HDAC7 around the non-phosphorylation site of Ser155. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | DKFZP586J0917,FLJ99588,HD 7a,HD7,HD7a,HDAC 7,HDAC 7A,Hdac7,HDAC7,HDAC7A,Histone deacetylase 7,Histone deacetylase 7A,OTTHUMP00000202813,OTTHUMP00000202814 |
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