GluR4 Polyclonal Antibody
- Catalog Number : A340533
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Introduction
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P48058 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human GluR4 around the non-phosphorylation site of Ser862. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | AMPA 4,AMPA selective glutamate receptor 4,AMPA-selective glutamate receptor 4,AMPA4,GluA 4,GluA4,GluR 4,GluR D,GluR-4,GluR-D,GluR4,GLUR4C,GLURD,Glutamate receptor 4,Glutamate receptor ionotrophic AMPA 4,Glutamate receptor ionotropic,GRIA 4,Gria4,GRIA4 |
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