BAX Polyclonal Antibody
- Catalog Number : A340445
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Introduction
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
General Information
Reactivity | Rat, Mouse |
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Application | WB, IF, ELISA |
Clonality | Polyclonal |
Conjugate | Non-conjugated |
Uniprot | Q07812 |
Isotype | IgG |
Immunogen | Synthesized peptide derived from human Bax around the non-phosphorylation site of Thr167. |
Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
Alias | Apoptosis regulator BAX,BAX,Bax-protein,BAX,BAXA,Baxdelta2G9,Baxdelta2G9omega,Baxdelta2omega,Bcl-2-like protein 4,BCL2 associated X protein,BCL2 associated X protein omega,BCL2 associated X protein transcript variant delta2,Bcl2-L-4,BCL2L4,membrane isoform alpha |