Phospho-BAD (Ser112) Polyclonal Antibody
- Catalog Number : A340195
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Introduction
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, IHC, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | Q92934 |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from human Bad around the phosphorylation site of Ser112 |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | BAD,BAD,BBC 2,BBC2,BBC6,Bcl 2 Antagonist of Cell Death,Bcl 2 Binding Component 6,BCL X / BCL 2 Binding Protein,BCL X Binding Protein,Bcl XL/Bcl 2 Associated Death Promoter,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl-XL/Bcl-2-associated death promoter,Bcl2 antagonist of cell death,BCL2 antagonist of cell death protein,BCL2 associated agonist of cell death,Bcl2 Associated Death Promoter,BCL2 binding component 6,BCL2 binding protein,Bcl2 Like 8 Protein,Bcl2-L-8,BCL2L8,Proapoptotic BH3 Only Protein |
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