RHOB Polyclonal Antibody
- Catalog Number : A340113
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Introduction
Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
General Information
| Reactivity | Rat, Mouse |
|---|---|
| Application | WB, ELISA |
| Clonality | Polyclonal |
| Conjugate | Non-conjugated |
| Uniprot | P62745 |
| Immunogen | Synthetic peptide of human RHOB |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3 |
| Storage instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Alias | Aplysia RAS-related homolog 6,ARH6,ARHB,H6,MST081,MSTP081,oncogene RHO H6,ras homolog family member B,ras homolog gene family,member B,Rho cDNA clone 6,Rho related GTP binding protein RhoB Precursor,Rho-related GTP-binding protein RhoB,Rhob,RHOB,RHOH6 |
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