Primary Antibody

FAK Polyclonal Antibody

  • Catalog Number : A340517
  • Number :
  • Size:
    Qty :
  • Price : Request Inquiry
  • print

Introduction

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

General Information

Reactivity Rat, Mouse
Application WB, IF, IHC, ELISA
Clonality Polyclonal
Conjugate Non-conjugated
Uniprot Q05397
Isotype IgG
Immunogen Synthesized peptide derived from human FAK around the non-phosphorylation site of Tyr397.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.3
Storage instruction Store at -20℃. Avoid freeze / thaw cycles.
Alias FADK 1,FADK,FAK related non kinase polypeptide,FAK1,FAK1,Focal adhesion kinase 1,Focal adhesion Kinase,Focal adhesion kinase isoform FAK Del33,Focal adhesion kinase related nonkinase,FRNK,p125FAK,pp125FAK,PPP1R71,Protein phosphatase 1 regulatory subunit 71,Protein tyrosine kinase 2,Protein-tyrosine kinase 2,Ptk2,PTK2 protein tyrosine kinase 2

Recently Viewed Products

gotop link
Customized Product Contact Us
0